GHK Copper Peptide Concentrate
Descrizione
GHK Copper Peptide Concentrate – Hair Regeneration and Follicular Vitality
GHK Copper Peptide Concentrate is an active ingredient in the form of a concentrated solution of Copper Tripeptide-1 in a vegetable glycerin base. This peptide complex, distinguished by its natural intense blue hue, is used in leading cosmetic formulations to improve the appearance and condition of the scalp. As a ready-to-use form, this concentrate allows for precise dosing and easy integration into hair and skin care preparations.
Ingredients (INCI): Glycerin, Aqua, Copper Tripeptide-1.
Technical Characteristics
- Active Substance Concentration: 50,000 ppm (5%) Copper Tripeptide-1.
- Appearance: Clear, cobalt blue liquid (no added colorants).
- Solubility: Completely water-soluble.
- Role: Skin and scalp conditioning agent.
Information from the Specialized Literature (GHK-Cu Substance)
Given that Copper Tripeptide-1 is a substance that has been extensively investigated in dermatological and trichological research, independent studies published in recent years have highlighted its remarkable potential:
- Modulation of Growth Factors: Recent studies indicate that GHK-Cu can influence the expression of growth factors in human dermal papilla cells, which are essential for follicle vitality.
- Support for the Hair Life Cycle: In the literature, the copper complex is frequently mentioned for its ability to support the growth (anagen) phases of hair strands.
- Antioxidant Protection at the Scalp Level: The molecule is recognized for its role in neutralizing free radicals, protecting follicles from oxidative stress that can accelerate premature hair aging.
- Revitalization and Density: Research suggests that topical application of copper peptides may improve the appearance of hair density by optimizing the root environment.
Recommendations for Use
General use level: 0.1%–1%.
Applications
- Scalp-care serums and lotions for density and vitality.
- Hair tonics designed to reduce the appearance of brittle hair.
- Professional scalp care products for use after invasive treatments.
- Fortifying shampoos; requires contact time with the scalp.
- Skin care creams and serums.
Formulation Guide
- Procedure: Add in the final stage of preparation, at temperatures below 40°C.
- Stability: Optimal pH 5.0-7.0; an overly acidic environment may lead to the dissociation of the copper ion from the peptide, compromising the efficacy and color of the product.
- Compatibility: Avoid simultaneous use in the same formula with strong chelating agents, acids, allantoin, niacinamide, arbutin, carbomer.
- Synergies: Works well with Biotinoyl Tripeptide-1, rosemary extract, maca root extract.
Frequently Asked Questions (FAQ)
Why is this product so blue?
The color comes exclusively from the natural interaction between peptides and copper ions.
Will the color affect the shade of blonde hair?
In the recommended dosages, the blue shade of the finished product is very diluted and does not produce residual coloring on the hair strands or scalp.
Usage Safety
Profile: Active ingredient for professional use and cosmetic formulation. Well tolerated in topical applications.
Precautions: For cosmetic use only. Do not ingest. Wear gloves when handling the pure concentrate. Keep out of reach of children.
Storage: Store in the original packaging, away from direct light, in a cool, dry place.
Bibliography and Reference Literature
- Song, K., et al. (2023). The effect of copper tripeptide-1 on the expressions of growth factors in human hair follicle dermal papilla cells. Journal of Cosmetic Dermatology.
- Pickart, L., & Margolina, A. (2023). The GHK Peptide: An Update on its Regenerative and Health-Promoting Actions. International Journal of Molecular Sciences.
- Dou, Y., et al. (2022). GHK-Cu: A versatile copper-peptide complex for biomedical applications. Biomedicine & Pharmacotherapy.
- Agrawal, A. S., et al. (2021). Peptides in Cosmeceuticals for Hair Care: A Review.
- Perez-Meza, D., et al. (2010). The role of copper peptides in hair transplantation. Hair Transplant Forum International.
- Pickart, L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition. (Secțiunea privind regenerarea foliculului pilos).
- Choi, H. I., et al. (2007). The peptide GHK-Cu promotes hair follicle enlargement and accelerates hair growth in mice. Journal of Dermatological Science.
- Pickart, L., & Margolina, A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences.
- Pickart, L., et al. (2015). GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International.
- Finkley, M. B., et al. (2005). Copper Peptide Complex: A Novel Skin Care Ingredient. In: Cosmetic Applications of Laser and Light-Based Systems.
- Badenhorst, T., et al. (2016). The role of copper peptides in cosmetic dermatology. Journal of Cosmetic Dermatology.
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